Leading Regeneration in Dental Biomaterials 

Geistlich has specialized in collagen and bone expertise for more than 170 years and has been committed to providing innovative and reliable solutions for clinicians who seek exceptional results while enhancing patient care.

Now Partnered with:

Why Choose Geistlich?

  • Complete Solutions: We offer everything you need for bone & soft-tissue regeneration—all from one trusted partner.
  • Assurance: Your assurance through our long-term evidence. Geistlich is scientifically proven in over 1400 publications.1
  • Proven Outcomes:  Over 15 million successfully treated patients worldwide. 1
  • Trustworthy: As the number one in regenerative dentistry worldwide, a Geistlich product is used every 15 seconds. 1
  • Comprehensive Support: We see ourselves as an extension of your team. From webinars and educational resources to regenerative specialists, we’re here to help you achieve the best results.

Everything you Need in One Regenerative Partner

For clinicians who seek exceptional results while elevating patient care, we provide efficient and proven solutions to achieve clinical and professional success.

Bio-Oss®-A xenograft that is Exactly Like No Other

  • An ideal environment for forming new bone:
    The unique inter-connecting pore structure is preserved through our patented technology, which allows for forming new bone.2
  • Volume Preservation:
    Slow resorbing properties provides long-term volume stability3
  • Implant Success:
    Geistlich Bio-Oss® ensures high implant survival4

Bio-Oss Collagen®- Bio-Oss® + 10% Collagen = Versatility

  • Unique Handling:
    Addition of 10% porcine collagen provides exceptional handling.
  • Ease of Use:
    Ability to adapt the material to the morphology of the defect and easily trim.
  • Improved Outcomes:
    Studies have shown less buccal dehiscences, increased horizontal bone volume, and improved soft-tissue healing when combining Geistlich Bio-Oss Collagen® + Geistlich Bio-Gide® vs DFDBA + a cross-linked membrane.6

vallos®- Allograft Solutions with The MTF Difference™

  • The most stringent donor selection: 
    Less than 2% of all donated tissue is accepted.7   
  • Rigorous incoming bioburden assessment:
    The only tissue bank that utilizes The Vanguard Method™ for quantitative and qualitative tissue testing and analysis – exceeding industry standards.  
  • 100% aseptic processing:
    Avoids the use of harsh chemicals and terminal irradiation that can compromise tissue integrity.

Bio-Gide® -Intelligently Designed to Guide Your Success

  • Unique Structures:
    A resorbable collagen membrane with a unique bilayer structure that permits prompt and homogeneous vascularization for optimal tissue integration and wound stabilization.8
  • Unsurpassed Handling:
    Excellent hydrophilicity promotes adhesion to the graft and surrounding bone, while the high tensile strength prevents tearing during handling.
  • Built for Regeneration:
    Supports new bone formation, tissue integration, and beneficial wound healing.8-13

Mucograft®- The Ideal Matrix for Gain of Keratinized Tissue and Recession Coverage

  • Design:
    Reconstituted collagen – no cross-linking. Provides a requisite reinforced matrix for regenerative wound healing.
  • Processing:
    Uniquely processed to encourage immediate blood clot stabilization.
  • Palate Free:
    Eliminates the need to harvest an autologous graft, significantly reduces post-operative pain and chair time.14-16

Fibro-Gide®- Ideal Matrix for Volume Stability

  • Volume Stability:
    The reconstituted collagen undergoes smart cross-linking for volume stability of the matrix17
  • Soft Tissue Formation:
    Animal models have shown good product integration into the surrounding soft tissue while maintaining stability18
  • Palate Free:
    Eliminates the need to harvest an autologous graft, significantly reduces post-operative pain and chair time.14-16
GEM 21S® Kit includes 0.5cc β-TCP/0.5 ml rhPDGF
 

GEM 21S®- Your key player in healing and bone formation

  • Consistency:
    The first and only off-the-shelf source of purified rhPDGF approved for bone and soft tissue regeneration.1
  • Faster Healing:
    Increases the amount of PDGF at the grafted site to aid in faster, more bone and better healing.19
  • Improved Outcomes:
    GEM 21S® is one of the most researched growth factors in dentistry. It has been proven to be safe and effective in regenerating bone and soft tissue in more than 500 publications and 60+ clinical studies.20

Meta® SafeScraper TWIST

SafeScraper TWIST provides an easy method for harvesting autogenous cortical bone for use in grafted sites with a minimally invasive technique.

For more information, contact your friendly Benco rep:
Call 1.800.GO.BENCO or visit benco.com.

Handling Videos

Handling Geistlich Bio-Oss®

Bio-Oss Collagen® Handling Video

vallos® Granules Handling Video

vallos® Fibers Handling Video

Geistlich Bio-Gide® Handling Video

Geistlich Mucograft® Handling Video

Geistlich Mucograft® Seal Handling Video

Geistlich Fibro-Gide® vs Geistlich Mucograft®

Geistlich Fibro-Gide® Introductory Training

Does it Matter
which bone substitute
you choose?

How does your bone substitute stack up?

How to Choose?

Because not all bone substitutes and manufacturers are created equal, there are several characteristics to consider that can lead to successful graft outcomes. How does your current bone substitute compare? Below are key characteristics to consider and why they are important:

Xenograft

Selecting the right xenograft with specific features is crucial for a successful outcome. What to consider:

Geistlich Bone
Substitute Portfolio

Your Current
Bone Substitute

Resorption Rate & Volume Stability

Once the tooth is gone, the alveolar bone resorbs over time. If the bony defect is augmented with a slow resorption bone substitute material, the volume of the augmented area will be preserved over the long-term yielding to stable functional and esthetic results.

The slow resorption of Geistlich Bio-Oss® and the ideally matched protective function of Geistlich Bio-Gide® promote the long-term volume stability1 of the augmentation material and ensure high implant survival rates.2

Processing Technique & Pore Structure

Processing is a critical factor to consider when choosing a bone substitutes manufacturer because it directly affects the quality, safety, and effectiveness of bone substitute products.

Geistlich Bio-Oss® undergoes a patented processing technique to preserve the natural integrity of the graft.

    Geistlich Bio-Oss Key Processing Steps:
  1. Cleaning
  2. Cutting
  3. Deproteinization
  4. Drying

This patented process leads to a unique interconnecting pore system, which is highly similar to human bone, an ideal environment for forming new bone.3

Handling Needs

For precision, ease of use, and adaptability, variation of handling properties is essential.

Geistlich offers a wide variety of handling needs from granules, to Geistlich Bio-Oss Collagen® to Geistlich Bio-Oss Pen®. Geistlich Bio-Oss Pen® enables you to access hard to reach areas of the mouth, while not compromising on ergonomics. Geistlich Bio-Oss Collagen® provides easy to hydrate and to position right in the defect area.

Allografts

When selecting an allograft, it is essential to consider various characteristics to ensure the best possible outcomes. What to consider:

Geistlich Bone
Substitute Portfolio

Your Current Bone
Substitute

Processing Matters

Processing is a critical factor to consider when choosing an allograft because it directly affects the quality, safety, and effectiveness of the tissue.

vallos® undergoes a unique patented processing technique to preserve the integrity of the graft.

    vallos® MTF Difference:
  1. Stringent Donor Selection — Less than 2% of all donated tissue is accepted.4
  2. Rigorous Testing — MTF is the only tissue bank to use The Vanguard Method® that exceeds industry standards.
  3. 100% Aseptic Processing — Preserves inherent biologic and structural properties. Leads to an unmatched tissue integrity and is naturally biocompatible with recipient.

Leads to the most natural tissue and exceptional biocompatibility with the recipient.

Variety of Configurations for the Right Indication

Flexibility within the portfolio to meet all your patient and surgical needs with the convenience of a single source provider.

By the numbers, Geistlich offers 35 allograft variations. vallos® consists of 9 configurations (four demineralized and five mineralized forms) in various cortical | cortico-cancellous | cancellous formulations.

Handling Needs

For precision, ease of use, and adaptability, variation of handling properties is essential.

Looking for handling? vallos®f demineralized Interwoven three dimensional fibers retain a putty like consistency that is packable and conforms to the shape of the defect.

Verified Osteoinductivity

Osteoinductivity of allografts can be impacted by both processing and sterilization methods, such as gamma irradiation which has been well documented to reduce the osteoinductive potential up to 50%.4 It is important that the osteoinductive potential is assessed post processing to ensure that it’s representative of the final product.5

Each and every lot of vallos® demineralized is tested for osteoinductivity potential, including BMP-2 post processing.

Manufacturer

The choice of manufacturer is an important consideration when selecting bone substitute because it directly impacts the quality, support, and reliability.

Geistlich Bone
Substitute Portfolio

Your Current Bone
Substitute

Manufacturing Ownership

Where is the bone substitute sourced?

Geistlich controls and manufactures Geistlich Bio-Oss® from the beginning to end. All vallos® allografts come from our single source provider, MTF, to ensure consistent product quality.

Long Term Clinical Evidence

Evaluating the success of a treatment is a function of time, so analyzing the companies’ long-term clinical evidence is critical in understanding the effectiveness of the bone substitutes.

Geistlich has led the guided bone regeneration world for more than 35 years, with 24+ years of independent clinical follow up.6

MTF brings 35+ years experience, 150,000+ tissue donors processed, and 10M grafts provided.

Discover our time-saving
scientific publications summaries

Peer-Reviewed Literature

Worldwide Independent research groups proving safety and efficacy of products and treatments.

Geistlich has more than 1,400 published peer-reviewed literature.

Cost-Benefit Analysis:

Analyze the cost-effectiveness of the bone substitute, taking into account the initial cost, potential complications, and the long-term benefits it offers compared to other treatment options.

Download our resource tool kit
for tips on protecting your
investment and cost breakdown.

Learning Opportunities and Resources

The ability to touch and feel the products, enhance your skills, and expertise to provide the assurance and continuous learning.

Courses & Congresses
Request Lunch & Learn

Key users

Key users can share data and insights about patient outcomes associated with various bone substitute products. This information is valuable in assessing the long-term effectiveness of different materials.

GROW with Geistlich
  1. Mordenfeld A et al.: Clin Oral Implants Res 2010; 21 (9), 961-70.
  2. Jung RE et al.: Clin Oral Implants Res 2013; 24 (10), 1065-73.
  3. Berglundh, T. et al. (1997). Clin Oral Implants Res. 8(2): 117–124.
  4. Data on file, MTF Biologics
  5. Gertzman AA, Sunwoo M, Raushi D, Dunn M. The Effect of Cold Gamma Radiation Sterilization on the Properties of Demineralised Bone Matrix. In: Kennedy JF, Philips GO, Williams PA, editors. Sterilization of tissues using ionising radiations: CRC Press; 2005. p 151-156.
  6. Jung R, et al., Clin Oral Implants Res 2021 Dec; 32(12):1455-1465.

The use of Geistlich Bio-Oss® resulted in significantly lower number of implant losses, compared to autogenous bone particles and other bone-graft materials.1

Resources

Bone Substitutes: Differentiating Properties Guide
Download
GPNA-Benco_TA-ProductGrid_2024_Final
Download
Product Portfolio
Download
Driving Dentistry Forward – Together
Download
Contact your Local Geistlich Representative
  1. Data on file, Geistlich Pharma AG, Wolhusen, Switzerland
  2. Weibrich, G. et al. (2000) Mund Kiefer Gesichtschirurg; 4(3): 148–52
  3. Mordenfeld, A. et al. (2010). Clin Oral Implants Res. 21(9):961–70
  4. Jung, R. et al. (2004). Int J Periodontics Restorative Dent. 24(6):545-53
  5. Knöfler W, et al., Int J Implant Dent. 2016 Dec; 2(1):25
  6. Scheyer et al. 2016
  7. Data on file, MTF Biologics®  
  8. Rothamel, D. et al. (2005). Clin Oral Implants Res. 16: 369-378
  9. Schwarz, F. et al. (2008). Clin Oral Implants Res. 19(4): 402-409.
  10. Wang, Y. et al. (2007). Ann NY Acad Sci. 1117: 1-11.
  11. Schwarz, F. et al. (2006). Clin Oral Implants Res. 17(4): 403-409.
  12. Becker, J. et al. (2009). Clin Oral Implants Res. 20(7): 742-749.
  13. Tahl, H. et al. (2008). Clin Oral Implants Res. 19(3): 295-302
  14. Thoma DS. et al. J Clin Periodontol. 2016 Oct; 43(10): 874–85 (clinical).
  15. Maiorana C. et al. (2016). Open Dent J. 22(10): 395-410.
  16. McGuire MK, Scheyer ET. (2016). J Periodontol. 87(3): 221-227.
  17. Instructions for Use. Geistlich Fibro-Gide®.Geistlich Pharma AG, Wolhusen, Switzerland.
  18. Thoma DS. et al. Clin Oral Implants Res. 2015 Mar; 26(3): 263–70 (pre-clinical)
  19. GEM 21S® Instructions for Use
  20. Data on file, Lynch Biologics, LLC